How Gluten Modifies your RNA

Alejo

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Hi everyone,

As I was going through the news tonight, I caught this short article in spanish that I wanted to share with you all, specially given the recent vaccination madness with AstraZeneca in Europe and the mRNA vaccines they're all trying to push forward.

Celiac disease is a complex autoimmune disorder that affects genetically susceptible individuals. Gluten in the diet triggers an immune response, for which the only treatment available so far is to follow a strict gluten-free diet for life. Following such a diet is not at all easy for patients, as it severely limits their quality of life. The difficulties in following such a strict diet can increase the risk of developing complications such as gastrointestinal cancers, so other treatments are needed to combat this disease. Although it has been proven that certain genes are related to genetic susceptibility to celiac disease, their role in the pathogenesis of the disease remains unknown, making it difficult to develop treatments.

A group from the Department of Genetics, Physical Anthropology and Animal Physiology of the University of the Basque Country (UPV/EHU) has been investigating the development of intestinal inflammation in celiac disease and in cases of gluten intolerance. As explained by Ainara Castellanos-Rubio, an Ikerbasque researcher, important results have been obtained in the study: "On the one hand, we have described for the first time that gluten modifies RNA molecules. These RNA modifications may be related to the development of diseases. Specifically, we have observed that gluten consumption by cells, mice and humans can modify the mRNA (messenger RNA) of the gene called XPO1, resulting in increased production of XPO1 proteins and increased inflammation in the intestine. On the other hand, a genetic variant included in the XPO1 gene has an impact on this RNA modification and increases the risk of developing intestinal inflammation in people with variable risk."

The study is entitled "Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells". It has been published in the journal Gut, one of the most important international journals in gastroenterology and hepatology, which publishes high-level clinical research. This research proposes new alternatives for treating celiac disease and other inflammatory bowel diseases: "Our research has described new therapeutic targets (such as XPO1 and proteins involved in RNA modification), and has opened the possibility of developing new therapeutic approaches to treat celiac disease. We are currently evaluating different molecules targeting these proteins and some are already being used to treat other intestinal diseases," explained Castellanos-Rubio.

On the other hand, and in terms of more basic science, the description of the modification that gluten can cause in RNA "opens new doors for research, since we have seen that external agents (such as gluten in the diet, in this case) can modify our RNA, giving rise to an inflammatory response," she says. In this sense, with a view to a more distant future, the researcher concludes that: "By adapting our diet or using dietary agents we may be able to modify RNA in one way or another, so as to slow down or prevent the development of certain diseases". (Source: UPV/EHU)

Translated with www.DeepL.com/Translator (free version)

Perhaps I am simply over sensitive to anything that mentions mRNA due to the vaccines, but think about it, Gluten, something we consume via our digestive system, which means it goes through several filters and we're fairly acquainted with, has the ability to alter our mRNA resulting in the development of inflammatory response and disease. Can you imagine what these vaccines, being injected directly into our cells, could do to humanity? specially if it's an already weekend human body?


Here's a link to the article on the Gut journal mentioned, just in case anyone is curious, I haven't checked it out myself: Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells | Gut
 
Well, the next question, I guess is - if gluten is able to modify the mRNA of the XPO1 gene, is it also able to modify the mRNA that is injected into people as a ‘vaccine’?
Or what effect would it have if combined, a debilitated body that has modified RNA that can cause autoimmune diseases due to Gluten consumption who then gets an mRNA vaccine, that's way too many variables for comfort.

Imagine that, a body that does not interact with the world as it naturally would, due to modified RNA, can become into an oven to turn regular everyday viruses for instance, into monstrosities.
 
Thank you Alejo for the information. Just today, I was rereading an article in sott, about the black plague. Among other things, more at the end of the article, it refers to the change in food and, it seems that the nobility, was hardly affected by the plague, because they consumed meat, and it was very expensive. If we bring this fact to the present day, we see that history may well repeat itself.

Here is an excerpt from the article:
"We know that the period between 500 and 1300 saw a major change in diet that affected most of Europe, a period that preceded the Black Death. Intensive agriculture, occupying more and more land, resulted in a shift from eating meat to eating various grains and vegetables as the staple food of the majority of the population. Meat was more expensive and therefore more prestigious and, usually in the form of game; it was common only on the tables of the nobility who, according to some chronicles, were hardly affected by the Black Death. So it could very well be that meat consumption is a nutritional protection against diseases of various kinds, including the Black Death (the archaeological record from the Paleolithic certainly supports this idea). We know that grains are sources of gluten, a protein that is quite difficult to digest and to which more and more people are intolerant because of its modern hybridization for industrial purposes. Anti-nutrients such as lectins in grains are known to be toxic. Wheat lectin is known to be pro-inflammatory, immunotoxic, neurotoxic, cytotoxic, cardiotoxic and can interfere with gene expression, alter endocrine function, can adversely affect gastrointestinal function and - surprise - lectins share pathogenic similarities with certain viruses [11] A population with bread as a staple food is certainly susceptible to disease and ultimately pandemic. As it was then, we are equally vulnerable today due to the industrialization of our food supply. Nutritionally deficient foods, plus the widespread consumption of grains, coupled with the overwhelming toxicity of our environment (heavy metals, fluoride, toxic food additives, etc.), have prepared us as a perfect population for destruction by the return of the Black Death."
 
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